Lithium levels in drinking water linked to higher risk of autism diagnosis in children.
A new study has found a moderate increase in the risk of autism spectrum disorder (ASD) in children born to pregnant women exposed to tap water with higher levels of lithium. However, experts say that this association does not necessarily imply a direct link between lithium exposure and ASD diagnosis.
According to the study published in the journal JAMA Pediatrics, the level of lithium in Danish drinking water is comparable to that found in American water systems. The researchers analyzed data from 8,842 children with ASD and 43,864 participants without ASD, who were born between 2000 and 2013. They found that as lithium levels in water increased, so did the risk of an ASD diagnosis.
The study's findings indicate a modest increase in risk for children exposed to higher levels of lithium during pregnancy. Specifically, those with second- and third-highest exposure levels had a 24% to 26% higher risk of ASD compared to those at the lowest level of exposure. The group with the highest exposure had a 46% higher risk.
However, experts caution that the research does not prove a direct causal link between lithium exposure and autism diagnosis. Dr. Beate Ritz, a co-author of the study, notes that further research is required to determine whether lithium exposure leads to ASD.
"It's essential to note that any drinking water contaminants affecting the developing human brain deserve intense scrutiny," Dr. Ritz said in a news release. "Replication of this study in other countries will be necessary to confirm the association."
Lithium levels in water have been linked to various health benefits, including lower rates of hospitalization for psychiatric disorders and suicide. However, the implications of these findings on public health policy are complex.
"It's like trying to solve a puzzle," said Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical School. "We need more research to distinguish causal from spurious associations."
Other studies have suggested connections between ASD and environmental exposures to pesticides, air pollution, and phthalates, but none have pinpointed any single factor as the direct cause.
"It's challenging to prove a link," said Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland. "We need to consider whether exposure to pollutants is causing ASD or if it's just populations living in more polluted areas."
Ultimately, determining the relationship between lithium exposure and autism diagnosis will require more research and careful analysis.
A new study has found a moderate increase in the risk of autism spectrum disorder (ASD) in children born to pregnant women exposed to tap water with higher levels of lithium. However, experts say that this association does not necessarily imply a direct link between lithium exposure and ASD diagnosis.
According to the study published in the journal JAMA Pediatrics, the level of lithium in Danish drinking water is comparable to that found in American water systems. The researchers analyzed data from 8,842 children with ASD and 43,864 participants without ASD, who were born between 2000 and 2013. They found that as lithium levels in water increased, so did the risk of an ASD diagnosis.
The study's findings indicate a modest increase in risk for children exposed to higher levels of lithium during pregnancy. Specifically, those with second- and third-highest exposure levels had a 24% to 26% higher risk of ASD compared to those at the lowest level of exposure. The group with the highest exposure had a 46% higher risk.
However, experts caution that the research does not prove a direct causal link between lithium exposure and autism diagnosis. Dr. Beate Ritz, a co-author of the study, notes that further research is required to determine whether lithium exposure leads to ASD.
"It's essential to note that any drinking water contaminants affecting the developing human brain deserve intense scrutiny," Dr. Ritz said in a news release. "Replication of this study in other countries will be necessary to confirm the association."
Lithium levels in water have been linked to various health benefits, including lower rates of hospitalization for psychiatric disorders and suicide. However, the implications of these findings on public health policy are complex.
"It's like trying to solve a puzzle," said Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical School. "We need more research to distinguish causal from spurious associations."
Other studies have suggested connections between ASD and environmental exposures to pesticides, air pollution, and phthalates, but none have pinpointed any single factor as the direct cause.
"It's challenging to prove a link," said Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland. "We need to consider whether exposure to pollutants is causing ASD or if it's just populations living in more polluted areas."
Ultimately, determining the relationship between lithium exposure and autism diagnosis will require more research and careful analysis.