Researchers in Germany have made significant progress in developing a nasal vaccine that can shut down Covid-19 infections before they even begin. The new approach takes advantage of the fact that the Covid-19 virus targets the upper airways, where mucosal immunity is crucial in preventing infection.
The vaccine, which uses a live but weakened form of the coronavirus, has been shown to create "sterilizing immunity" in hamsters by blocking the virus from copying itself in the animals' upper airways. This means that even if the hamsters are infected with the Omicron variant, the vaccine can still neutralize the virus and prevent illness.
The nasal vaccine is unique because it previews the entire coronavirus for the body, not just its spike proteins like current vaccines do. This allows the immune system to make antibodies against a wider range of targets, which could potentially provide longer-lasting protection.
While the results are promising, experts caution that more testing is needed before the vaccine can be widely used. The US has reached a "stalemate" with Covid-19, with hundreds of Americans still dying daily from the infection.
The development of nasal vaccines is an area where significant progress has been made in recent months. Several other nasal vaccines are nearing completion in clinical trials, including one developed by Codagenix that uses a live but weakened version of the virus.
However, experts also warn that respiratory infections can be tough targets for inhaled vaccines, and it's unclear how well these new nasal vaccines will work in humans. Additionally, people with compromised immunity may need to exercise caution when using live vaccines like this one.
The German team is eager to see the results of Codagenix's studies later this year, which could provide valuable insights into the effectiveness of nasal vaccines. While there are still many hurdles to clear before these new vaccines can be widely available, they offer a promising approach to preventing Covid-19 infections and could potentially provide longer-lasting protection against the virus.
				
			The vaccine, which uses a live but weakened form of the coronavirus, has been shown to create "sterilizing immunity" in hamsters by blocking the virus from copying itself in the animals' upper airways. This means that even if the hamsters are infected with the Omicron variant, the vaccine can still neutralize the virus and prevent illness.
The nasal vaccine is unique because it previews the entire coronavirus for the body, not just its spike proteins like current vaccines do. This allows the immune system to make antibodies against a wider range of targets, which could potentially provide longer-lasting protection.
While the results are promising, experts caution that more testing is needed before the vaccine can be widely used. The US has reached a "stalemate" with Covid-19, with hundreds of Americans still dying daily from the infection.
The development of nasal vaccines is an area where significant progress has been made in recent months. Several other nasal vaccines are nearing completion in clinical trials, including one developed by Codagenix that uses a live but weakened version of the virus.
However, experts also warn that respiratory infections can be tough targets for inhaled vaccines, and it's unclear how well these new nasal vaccines will work in humans. Additionally, people with compromised immunity may need to exercise caution when using live vaccines like this one.
The German team is eager to see the results of Codagenix's studies later this year, which could provide valuable insights into the effectiveness of nasal vaccines. While there are still many hurdles to clear before these new vaccines can be widely available, they offer a promising approach to preventing Covid-19 infections and could potentially provide longer-lasting protection against the virus.
 I'm super excited about this nasal vaccine news!
 I'm super excited about this nasal vaccine news!  It's amazing how researchers in Germany have been able to create a live but weakened version of the coronavirus that can prevent Covid-19 infections before they even start. The fact that it previews the entire coronavirus for our bodies is huge, and I'm all about wider immunity
 It's amazing how researchers in Germany have been able to create a live but weakened version of the coronavirus that can prevent Covid-19 infections before they even start. The fact that it previews the entire coronavirus for our bodies is huge, and I'm all about wider immunity  . I know there are still some concerns about testing and effectiveness, but this gives me hope for a better future where we don't have to live with the constant worry of Covid-19
. I know there are still some concerns about testing and effectiveness, but this gives me hope for a better future where we don't have to live with the constant worry of Covid-19  . Can you imagine being able to travel or hang out with friends without having to wear masks?
. Can you imagine being able to travel or hang out with friends without having to wear masks? 
 This is like something out of that movie Contagion
 This is like something out of that movie Contagion  , you know? Developing a vaccine that can shut down the virus before it even takes hold? That's some sci-fi stuff right there!
, you know? Developing a vaccine that can shut down the virus before it even takes hold? That's some sci-fi stuff right there!  But seriously, I'm glad to see researchers in Germany making progress on this nasal vaccine. It makes sense that targeting the upper airways is key to preventing infection. And the fact that it previews the entire coronavirus instead of just its spike proteins could be a game-changer for long-term protection
 But seriously, I'm glad to see researchers in Germany making progress on this nasal vaccine. It makes sense that targeting the upper airways is key to preventing infection. And the fact that it previews the entire coronavirus instead of just its spike proteins could be a game-changer for long-term protection 
 . And what about those who've already been infected? Will this vaccine give them immunity or just prevent new strains from emerging?
. And what about those who've already been infected? Will this vaccine give them immunity or just prevent new strains from emerging?  We need to see more studies on that before we get too hyped
 We need to see more studies on that before we get too hyped  .
. I'm loving the idea of this nasal vaccine that can stop the virus before it even starts to cause trouble. It's like our bodies have a special force field built-in, and this vaccine just helps boost those defenses
 I'm loving the idea of this nasal vaccine that can stop the virus before it even starts to cause trouble. It's like our bodies have a special force field built-in, and this vaccine just helps boost those defenses 
 Still, the fact that it previews the whole coronavirus instead of just its spike proteins is a game-changer. That means our bodies will have a broader range of protection against Covid-19, which could lead to some serious long-term benefits
 Still, the fact that it previews the whole coronavirus instead of just its spike proteins is a game-changer. That means our bodies will have a broader range of protection against Covid-19, which could lead to some serious long-term benefits  Codagenix's study later this year is gonna be super interesting to see. Fingers crossed these new nasal vaccines become a reality soon and help us move past Covid-19
 Codagenix's study later this year is gonna be super interesting to see. Fingers crossed these new nasal vaccines become a reality soon and help us move past Covid-19 
 ! I mean, it's awesome that German researchers have made such progress with it. The fact that it can create 'sterilizing immunity' in hamsters is mind-blowing
! I mean, it's awesome that German researchers have made such progress with it. The fact that it can create 'sterilizing immunity' in hamsters is mind-blowing  . And the idea that it previews the entire coronavirus for the body instead of just its spike proteins is a game-changer
. And the idea that it previews the entire coronavirus for the body instead of just its spike proteins is a game-changer  we've been dealing with Covid-19 for years now! We need all the help we can get. And I love how the US is reaching out to Codagenix's studies
 we've been dealing with Covid-19 for years now! We need all the help we can get. And I love how the US is reaching out to Codagenix's studies 
 I'm so relieved to hear about this new nasal vaccine that might just give us all some peace of mind... it's been such a long and scary journey with Covid-19, and we've lost so many people who shouldn't have had to go through that
 I'm so relieved to hear about this new nasal vaccine that might just give us all some peace of mind... it's been such a long and scary journey with Covid-19, and we've lost so many people who shouldn't have had to go through that  . The fact that this vaccine could potentially provide longer-lasting protection is just amazing - can you imagine being able to travel or hang out with friends without worrying about getting sick?
. The fact that this vaccine could potentially provide longer-lasting protection is just amazing - can you imagine being able to travel or hang out with friends without worrying about getting sick? 
 ! I'm so curious about how it works - basically, the virus targets the upper airways where mucosal immunity kicks in? Mind blown
! I'm so curious about how it works - basically, the virus targets the upper airways where mucosal immunity kicks in? Mind blown  . And the fact that it previews the entire coronavirus instead of just its spike proteins is genius
. And the fact that it previews the entire coronavirus instead of just its spike proteins is genius  . But at the same time, experts are warning us to be cautious because respiratory infections can be tricky to tackle... what if it doesn't work for people with compromised immunity?
. But at the same time, experts are warning us to be cautious because respiratory infections can be tricky to tackle... what if it doesn't work for people with compromised immunity? 
 . It's got potential to provide longer-lasting protection, which would be a game-changer for people who've been living with this thing for years
. It's got potential to provide longer-lasting protection, which would be a game-changer for people who've been living with this thing for years  .
. . If they show promising results, it could be a major breakthrough in the fight against COVID-19
. If they show promising results, it could be a major breakthrough in the fight against COVID-19  . i mean, the current ones are just not doing their job if you ask me. this nasal thingy is like a game changer
. i mean, the current ones are just not doing their job if you ask me. this nasal thingy is like a game changer  . it can shut down covid before it even starts? thats sick
. it can shut down covid before it even starts? thats sick  . but yeah, more testing is needed and all that jazz. cant have ppl dying from covid still while we wait for the next big breakthrough
. but yeah, more testing is needed and all that jazz. cant have ppl dying from covid still while we wait for the next big breakthrough  Like, our noses are basically the first line of defense against all the nasty stuff that enters our bodies. And I love how this new vaccine uses a live but weakened form of the coronavirus - it's like giving your immune system a little nudge in the right direction!
 Like, our noses are basically the first line of defense against all the nasty stuff that enters our bodies. And I love how this new vaccine uses a live but weakened form of the coronavirus - it's like giving your immune system a little nudge in the right direction!  . And don't even get me started on the idea of "sterilizing immunity" – is that even a real thing? How do we know it won't have some unforeseen side effects?
. And don't even get me started on the idea of "sterilizing immunity" – is that even a real thing? How do we know it won't have some unforeseen side effects?  is it supposed to be less painful or something?
 is it supposed to be less painful or something? 
 I mean, it's not like we haven't tried everything else before!
 I mean, it's not like we haven't tried everything else before!  . I mean, hundreds of people still dyin' from Covid every day? That's crazy
. I mean, hundreds of people still dyin' from Covid every day? That's crazy  . But at the same time, if it can prevent infections before they even happen, that'd be a game-changer
. But at the same time, if it can prevent infections before they even happen, that'd be a game-changer  . And the fact that it previews the whole coronavirus instead of just its spike proteins is like, super clever
. And the fact that it previews the whole coronavirus instead of just its spike proteins is like, super clever  .
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