Popular Herbal Supplements Linked to Liver Injury and Other Health Issues
For decades, herbal supplements have been touted as a natural way to improve health and reduce the risk of chronic diseases. However, a growing number of cases are revealing that these so-called "miracle cures" can actually cause serious harm.
Take the case of Fernanda Thompson, a 40-year-old Florida woman who began taking turmeric in an effort to boost her immunity during COVID-19. What started as a harmless addition to her morning smoothie quickly turned into a nightmare when she was diagnosed with low white blood cell count and liver enlargement.
Thompson's story is not unique. According to experts, millions of Americans take potentially toxic compounds on a daily basis, including turmeric, ashwagandha, and green tea extract. In fact, research suggests that 15.6 million Americans are taking these substances without proper knowledge or regulation.
The problem is that the liver's normal detoxification functions can be overwhelmed by these compounds, leading to serious health issues. "It's more common now to see some severe cases of liver injury end up in the hospital," says Dr. Alisa Likhitsup, a gastroenterology and transplant hepatologist at the University of Michigan.
While some people may not experience any adverse effects from taking herbal supplements, others can suffer from severe symptoms such as abdominal pain, fevers, fatigue, and jaundice. In extreme cases, liver failure can even lead to death.
The reasons behind these unpredictable reactions are still not fully understood, but researchers believe that genetics play a significant role. "We do find unique genetic susceptibility factors among people who get liver injury," says Dr. Robert Fontana, a leading global authority on drug-induced liver disease.
Fontana's team has been studying the effects of herbal supplements on the liver since 2004 and has documented a growing trend of liver injuries linked to these substances. In 2022 alone, cases of drug-induced liver failure requiring waitlisting for liver transplantation due to herbal dietary supplements increased eightfold.
While it may seem unlikely that herbal supplements can cause harm, experts warn that even small doses can have significant effects. "You're playing Russian roulette with your genetic ability to tolerate it," says Fontana.
In recent years, there have been several high-profile cases of people becoming seriously ill after taking ashwagandha and other herbal supplements. One case involved a 46-year-old former lawyer who developed severe liver inflammation and was hospitalized for several weeks.
While these stories are alarming, experts stress that most supplements are unnecessary and that proper nutrition can provide the same benefits without the risk of adverse effects. "Proper nutrition is best achieved through diet," says Dr. Qianzhi Jiang, a registered dietitian based near Boston.
In light of these concerns, experts are calling for greater regulation and education on herbal supplements. "There's very few physicians out there that are well-educated on drug-induced liver injury and the harmful impact of supplements," says Kathuria, the former lawyer who suffered from ashwagandha toxicity.
As the popularity of herbal supplements continues to grow, it's essential that consumers take a closer look at what they're putting into their bodies. "The fact that it's a plant doesn't mean it's effective or safe," warns Fernanda Thompson, who wishes she had never taken turmeric in the first place.
For decades, herbal supplements have been touted as a natural way to improve health and reduce the risk of chronic diseases. However, a growing number of cases are revealing that these so-called "miracle cures" can actually cause serious harm.
Take the case of Fernanda Thompson, a 40-year-old Florida woman who began taking turmeric in an effort to boost her immunity during COVID-19. What started as a harmless addition to her morning smoothie quickly turned into a nightmare when she was diagnosed with low white blood cell count and liver enlargement.
Thompson's story is not unique. According to experts, millions of Americans take potentially toxic compounds on a daily basis, including turmeric, ashwagandha, and green tea extract. In fact, research suggests that 15.6 million Americans are taking these substances without proper knowledge or regulation.
The problem is that the liver's normal detoxification functions can be overwhelmed by these compounds, leading to serious health issues. "It's more common now to see some severe cases of liver injury end up in the hospital," says Dr. Alisa Likhitsup, a gastroenterology and transplant hepatologist at the University of Michigan.
While some people may not experience any adverse effects from taking herbal supplements, others can suffer from severe symptoms such as abdominal pain, fevers, fatigue, and jaundice. In extreme cases, liver failure can even lead to death.
The reasons behind these unpredictable reactions are still not fully understood, but researchers believe that genetics play a significant role. "We do find unique genetic susceptibility factors among people who get liver injury," says Dr. Robert Fontana, a leading global authority on drug-induced liver disease.
Fontana's team has been studying the effects of herbal supplements on the liver since 2004 and has documented a growing trend of liver injuries linked to these substances. In 2022 alone, cases of drug-induced liver failure requiring waitlisting for liver transplantation due to herbal dietary supplements increased eightfold.
While it may seem unlikely that herbal supplements can cause harm, experts warn that even small doses can have significant effects. "You're playing Russian roulette with your genetic ability to tolerate it," says Fontana.
In recent years, there have been several high-profile cases of people becoming seriously ill after taking ashwagandha and other herbal supplements. One case involved a 46-year-old former lawyer who developed severe liver inflammation and was hospitalized for several weeks.
While these stories are alarming, experts stress that most supplements are unnecessary and that proper nutrition can provide the same benefits without the risk of adverse effects. "Proper nutrition is best achieved through diet," says Dr. Qianzhi Jiang, a registered dietitian based near Boston.
In light of these concerns, experts are calling for greater regulation and education on herbal supplements. "There's very few physicians out there that are well-educated on drug-induced liver injury and the harmful impact of supplements," says Kathuria, the former lawyer who suffered from ashwagandha toxicity.
As the popularity of herbal supplements continues to grow, it's essential that consumers take a closer look at what they're putting into their bodies. "The fact that it's a plant doesn't mean it's effective or safe," warns Fernanda Thompson, who wishes she had never taken turmeric in the first place.