Higher lithium levels in drinking water may be linked to an increased risk of autism spectrum disorder (ASD) in children, according to a new study published Monday in the journal JAMA Pediatrics. Researchers analyzed data from over 8,800 children born between 2000 and 2013 in Denmark, where the average level of lithium in tap water is relatively low compared to other countries.
The study found that pregnant women exposed to higher levels of lithium through their drinking water had a modestly increased risk of having a child diagnosed with ASD. Specifically, those with the highest exposure levels had a 46% greater risk than those at lower exposure levels.
While the association between lithium exposure and autism is intriguing, experts caution that it does not necessarily prove a direct link. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," said Dr. Beate Ritz, co-author of the study. However, further research is needed to confirm the findings.
The implications of this association are complex and would require careful consideration in public health policy. Lithium levels in tap water have also been linked with reduced hospitalization rates for psychiatric disorders and lower suicide rates.
Other studies have suggested connections between ASD and environmental exposures, such as pesticides, air pollution, and phthalates. However, none have proven a direct cause-and-effect link.
"We need to be cautious not to jump to conclusions," said Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland. "We're bombarded with environmental stressors, and we need to figure out how to safely navigate them."
The study highlights the importance of ongoing research into potential environmental causes of ASD. While more work is needed, it is essential to investigate any associations between drinking water contaminants and neurological disorders.
The study found that pregnant women exposed to higher levels of lithium through their drinking water had a modestly increased risk of having a child diagnosed with ASD. Specifically, those with the highest exposure levels had a 46% greater risk than those at lower exposure levels.
While the association between lithium exposure and autism is intriguing, experts caution that it does not necessarily prove a direct link. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," said Dr. Beate Ritz, co-author of the study. However, further research is needed to confirm the findings.
The implications of this association are complex and would require careful consideration in public health policy. Lithium levels in tap water have also been linked with reduced hospitalization rates for psychiatric disorders and lower suicide rates.
Other studies have suggested connections between ASD and environmental exposures, such as pesticides, air pollution, and phthalates. However, none have proven a direct cause-and-effect link.
"We need to be cautious not to jump to conclusions," said Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland. "We're bombarded with environmental stressors, and we need to figure out how to safely navigate them."
The study highlights the importance of ongoing research into potential environmental causes of ASD. While more work is needed, it is essential to investigate any associations between drinking water contaminants and neurological disorders.